Anita Falezza

Title: Anita Falezza: Innovator in Pharmaceutical Chemistry

Introduction

Anita Falezza is a notable inventor based in Pomezia, Italy. She has made significant contributions to the field of pharmaceutical chemistry, particularly in the preparation of zofenopril calcium salt. With a total of 2 patents, her work has advanced the understanding and application of this important compound.

Latest Patents

Anita's latest patents focus on the process for the preparation of zofenopril calcium salt. The first patent describes a method that involves the reaction of S(−)-3-benzoylthio-2-methylpropanoic acid chloride with cis-4-phenylthio-L-proline in water at a pH ranging from 9.0 to 9.5. This process allows for the recovery of zofenopril in its acidic form. The subsequent steps include salification of the acid zofenopril with a potassium salt in an alcoholic solution, followed by the conversion of the potassium salt to the calcium salt through a carefully controlled reaction with CaCl aqueous solution at elevated temperatures.

Career Highlights

Anita has worked with prominent companies in the pharmaceutical industry, including Menarini Ricerche S.p.A. and Menarini Richerche S.p.A. Her expertise in the field has led to innovative solutions that enhance the efficacy and purity of pharmaceutical compounds.

Collaborations

Throughout her career, Anita has collaborated with esteemed colleagues such as Raffaello Giorgi and Antonio Giachetti. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of knowledge.

Conclusion

Anita Falezza's contributions to pharmaceutical chemistry, particularly through her patents on zofenopril calcium salt, highlight her role as a leading inventor in her field. Her work continues to influence the development of effective pharmaceutical solutions.