Aniruddha Sinha

Title: Innovations by Aniruddha Sinha in the Field of Myocardial Ischemia

Introduction

Aniruddha Sinha is a prolific inventor based in Kolkata, India, with an impressive portfolio of 61 patents. His contributions primarily focus on advancements in the medical technology sector, particularly related to cardiac health. Sinha's innovative methodologies offer new insights into the diagnosis and classification of myocardial ischemia, a condition affecting many patients globally.

Latest Patents

Among Aniruddha Sinha's latest patents is a groundbreaking "Method and system for determining myocardial ischemia severity based on hemodynamic parameters estimation." This innovative approach addresses a critical need for accurate assessment of myocardial ischemia resulting from narrowed coronary arteries, leading to inadequate oxygen supply to cardiac muscles. The method involves the reception of Electrophysiology (EP) signals from a simulated heart surface model to create a single lead ECG template. Utilizing this template, hemodynamic parameters are then estimated, allowing the determination of cardiac pressure-volume loop variables. The output provides a clear classification of ischemia severity, categorizing it into moderate, severe, or silent ischemia, ultimately serving as a vital tool for patient care and disease classification.

Another significant patent is the "Method and system for generating synthetic time domain signals to build a classifier." This innovative system addresses limitations in current methods that generate synthetic biosignals by providing a more accurate representation of patient-specific PPG signatures without correlating with pathophysiological changes. Through statistical explosion, Sinha’s method creates synthetic time domain signals, utilizing a parent dataset to extract statistical features and employing Kernel Density Estimate (KDE) to create diverse data templates from single signals. The generated synthetic dataset effectively supports a two-stage cascaded classifier that distinguishes between Coronary Artery Disease (CAD) and Non-CAD, thereby reducing biases in classification.

Career Highlights

Aniruddha Sinha has collaborated with esteemed organizations such as Tata Consultancy Services Limited and the Indian Statistical Institute. His work in these companies allowed him to refine his expertise and contribute to significant advancements in statistical and technical methodologies used in the health sector.

Collaborations

Throughout his career, Aniruddha has worked alongside notable colleagues including Arpan Pal and Debatri Chatterjee. Their collaborative efforts have likely enhanced the development and implementation of cutting-edge technologies within his research initiatives.

Conclusion

Aniruddha Sinha’s dedicated work in the realm of cardiac health innovation is commendable. With 61 patents to his name, his methods for assessing myocardial ischemia and generating synthetic biosignals mark significant advancements in medical technology. As he continues to drive innovation, his contributions pave the way for improved patient outcomes and more accurate disease classification methods.