This inventor holds 3 USPTO granted patents and 2 published patent applications and 3 EPO patents. Top assignee: Nanyang Technological University. Active years: 2017-2022.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2017-2022
Title: Innovations of Anh Tuan Phan in Antisense Oligonucleotide Research
Introduction
Anh Tuan Phan is a prominent inventor based in Singapore, known for his significant contributions to the field of molecular biology and antisense oligonucleotide research. With a total of 3 patents, his work focuses on innovative methods and applications that enhance the stability and efficacy of nucleic acid molecules.
Latest Patents
One of his latest patents is titled "G-quadruplex-containing antisense oligonucleotides." This invention relates to conjugates that comprise an antisense oligonucleotide (ASO) and at least one G-quadruplex structure. The ASO and the G-quadruplex structure are heterologous to each other, allowing for enhanced properties such as potency and therapeutic index. The conjugates are designed for use as medicaments, providing methods for modulating the stability, translation, splicing, cleavage, or activity of target nucleic acid molecules.
Another notable patent is "Site-specific induction of bimolecular quadruplex-duplex hybrids and methods of using the same." This method presents a way to generate a G-quadruplex structure on a target nucleic acid sequence. It combines the specificity of Watson-Crick base pairing with the stability of a robust G-quadruplex scaffold. The induction of these hybrids can be applied in antigene or antisense contexts, offering enhanced steric blockage to transcriptional or translational machinery.
Career Highlights
Anh Tuan Phan is affiliated with Nanyang Technological University, where he conducts research and develops innovative solutions in the field of molecular biology. His work has garnered attention for its potential applications in therapeutic settings.
Collaborations
He has collaborated with notable colleagues, including Brahim Heddi and Vee Vee Cheong, contributing to advancements in their shared research interests.
Conclusion
Anh Tuan Phan's innovative work in the field of antisense oligonucleotides and G-quadruplex structures showcases his commitment to advancing molecular biology. His patents reflect a deep understanding of nucleic acid interactions and their potential therapeutic applications.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile