This inventor holds 3 USPTO granted patents, plus 1 CIPO patent and 1 EPO patent. Top assignee: Trustees of the Colorado School of Mines. Active years: 2001-2011.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Denver, CO (US) (2001)
- Tooele, UT (US) (2007 - 2011)
Company Filing History:
Years Active: 2001-2011
Title: Angelo J. Madonna: Innovator in Bacterial Detection Technologies
Introduction
Angelo J. Madonna, an accomplished inventor based in Tooele, UT, has made significant contributions to the field of microbiology through his innovative patents. With a total of three patents to his name, his work focuses on advancing techniques for detecting bacteria in various liquid solutions.
Latest Patents
Among his latest inventions is a method for detecting low concentrations of target bacteria by utilizing bacteriophages to infect target bacterial cells. This invention outlines a systematic process that begins with immunomagnetic separation (IMS) to isolate the target bacterium from a complex liquid mixture. Following this separation, a low concentration of bacteriophage is introduced to infect the captured bacterial cells. When the target bacteria reach a specific concentration, the bacteriophage multiplies to levels that can be detected. The final step employs Matrix-Assisted Laser Desorption Ionization/Time-of-Flight Mass Spectrometry (MALDI/TOF-MS) to generate a mass spectrum for analysis. This helps to ascertain the presence of proteins associated with the bacteriophage, indirectly indicating the presence of the target bacteria in the original liquid mixture.
Career Highlights
Angelo currently works at the Trustees of the Colorado School of Mines, where he continues to develop innovative solutions in biotechnology and microbiology. His contributions have played a crucial role in enhancing detection methods that are vital for various applications, including environmental monitoring and public health.
Collaborations
Throughout his career, Angelo has collaborated with notable colleagues, including Kent J. Voorhees and Jon C. Rees. These collaborations have enriched his research and expanded the impact of his innovative inventions, fostering a multidisciplinary approach to solving complex scientific problems.
Conclusion
Angelo J. Madonna's inventive spirit and commitment to advancing bacterial detection technologies position him as a noteworthy figure in the field of microbiology. His patents not only demonstrate his expertise but also contribute significantly to technological advancements that benefit health and environmental safety.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
