Angela Wandinger-Ness

Title: Angela Wandinger-Ness: Innovator in GTPase Modulation

Introduction

Angela Wandinger-Ness is a prominent inventor based in Albuquerque, NM (US), known for her significant contributions to the field of molecular biology and therapeutic innovations. With a total of 12 patents to her name, she has made remarkable strides in understanding and manipulating GTPases, which play crucial roles in various diseases.

Latest Patents

Her latest patents include groundbreaking work on modulators of GTPases and their applications in treating diseases such as cancers and genetic disorders. One notable invention focuses on molecules that act as inhibitors and agonists of the Ras-homologous (Rho) family of small GTPases, including Rac, Cdc42, and Rho GTPases. These molecules are designed to target diseases where these GTPases are overexpressed or hyperactivated, such as medulloblastoma, ovarian cancer, and Alzheimer's disease. Additionally, she has developed methods for diagnosing sepsis and virus-related infections through the detection of specific GTPase biomarkers, utilizing multiplexed flow cytometry.

Career Highlights

Angela has worked with notable organizations, including UNM Rainforest Innovations and STC.UNM, where she has contributed to advancing research and innovation in her field. Her work has not only led to numerous patents but has also paved the way for new therapeutic approaches to complex diseases.

Collaborations

Throughout her career, Angela has collaborated with esteemed colleagues, including Larry A. Sklar and Zurab Surviladze, enhancing the impact of her research through shared expertise and innovation.

Conclusion

Angela Wandinger-Ness exemplifies the spirit of innovation in the scientific community, with her patents reflecting a commitment to addressing critical health challenges through advanced research in GTPase modulation. Her contributions continue to influence the landscape of molecular therapeutics and diagnostics.