Company Filing History:
Years Active: 1988
Title: Angela M O'Toole: Innovator in Luminescent Assays
Introduction
Angela M O'Toole is a notable inventor based in Wolverhampton, GB. She has made significant contributions to the field of assay technology, particularly through her innovative work on luminescent assays. Her research has focused on enhancing the sensitivity of chemiluminescent emissions, which are crucial for various assay applications.
Latest Patents
Angela holds a patent for an "Enhanced luminescent or luminometric assay." This invention addresses the common issue of weak chemiluminescent emissions produced during the peroxidase-catalyzed oxidation of 2,3-dihydro-1,4-phthalazinedione. The invention identifies certain narrowly defined aromatic amines as enhancers of the reaction, thereby improving the signal-background ratio and sensitivity required for assays, such as those used in ELISA.
Career Highlights
Angela is currently associated with the National Research Development Corporation, where she continues to advance her research in assay technologies. Her work has been instrumental in developing more effective diagnostic tools that can benefit various scientific and medical fields.
Collaborations
Angela has collaborated with esteemed colleagues, including Larry J Kricka and Gary H Thorpe, who have contributed to her research endeavors and the development of her patented technologies.
Conclusion
Angela M O'Toole's innovative contributions to luminescent assay technology highlight her role as a leading inventor in her field. Her work not only addresses significant challenges in assay sensitivity but also paves the way for advancements in diagnostic applications.