Angela Jo Gruber

Title: **Angela Jo Gruber: Innovator in Site-Specific DNA Cleavage**

Introduction

Angela Jo Gruber, based in Madison, WI, has made significant contributions to the field of biotechnology. As an inventor with a focus on genetic engineering, she has been recognized for her innovative work in DNA manipulation.

Latest Patents

Angela holds a notable patent titled "REF nuclease for site-specific REF-mediated DNA cleavage." This patent encompasses the purification of Ref polypeptides that exhibit increased nuclease site-specific targeting activity, alongside recombinant nucleic acids and cells for their expression. Moreover, it details methods for utilizing Ref polypeptides in conjunction with RecA protein and its variants for the targeted cleavage of DNA duplexes.

Career Highlights

With one patent to her name, Angela has established herself as a prominent figure in her field. Her research and findings have the potential to revolutionize techniques in genetic engineering, providing tools for more precise DNA manipulation.

Collaborations

Angela has worked alongside notable colleagues, including Michael Matthew Cox and Tayla Maria Olsen. These collaborations reflect her integrated approach to innovation, drawing on the strengths and expertise of her peers to advance her research.

Conclusion

Angela Jo Gruber exemplifies the spirit of innovation in the realm of biotechnology. Her contributions, particularly through her patent on targeted DNA cleavage, highlight the importance of female inventors in a field that continually shapes the future of science and technology.