Angel Alfonso Cruz Roa

Title: Innovations by Angel Alfonso Cruz Roa

Introduction

Angel Alfonso Cruz Roa is an accomplished inventor based in Villavicencio, Colombia. He has made significant contributions to the field of histopathology through his innovative patents. With a total of 2 patents, his work focuses on improving the analysis of tissue samples, particularly in cancer diagnosis.

Latest Patents

One of his latest patents is titled "High-throughput adaptive sampling for whole-slide histopathology image analysis." This invention involves methods and apparatuses for classifying regions of tissue represented in digitized whole slide images (WSI) using iterative gradient-based quasi-Monte Carlo (QMC) sampling. The apparatus includes an image acquisition circuit that captures a WSI of tissue demonstrating cancerous pathology. An adaptive sampling circuit selects a subset of tiles from the WSI using an iterative QMC Sobol sequence sampling approach. Additionally, an invasiveness circuit determines the probability of invasive pathology in the selected tiles. A probability map circuit generates an invasiveness probability map based on this probability, while a probability gradient circuit creates a gradient image based on the invasiveness probability map. Finally, a classification circuit classifies the region of tissue based on the probability map, allowing for the provision of a prognosis or treatment plan based on the classification of the WSI.

Career Highlights

Angel Alfonso Cruz Roa is affiliated with Case Western Reserve University, where he continues to advance his research and innovations in histopathology. His work has garnered attention for its potential to enhance diagnostic accuracy and treatment planning in cancer care.

Collaborations

He collaborates with notable colleagues such as Fabio Gonzalez and Anant Madabhushi, contributing to a dynamic research environment focused on medical imaging and pathology.

Conclusion

Angel Alfonso Cruz Roa's innovative work in histopathology exemplifies the impact of technology on medical diagnostics. His contributions are paving the way for more effective cancer detection and treatment strategies.