Company Filing History:
Years Active: 2011
Title: Anel Oostheysen: Innovator in Bioprosthetic Tissue Preparation
Introduction
Anel Oostheysen is a notable inventor based in Cape Town, South Africa. He has made significant contributions to the field of bioprosthetic tissue preparation, particularly through his innovative methods involving synthetic hydrogels. His work aims to enhance the longevity and functionality of xenogenic tissues used in human implantation.
Latest Patents
Anel Oostheysen holds a patent for a bioprosthetic tissue preparation method that utilizes synthetic hydrogels. This patent outlines methods for treating xenogenic tissue for implantation into the human body, including in-situ polymerization of a hydrogel polymer in tissue that has not been fixed with glutaraldehyde. The polymerization process can fill the tissue, bind the polymer to the tissue, or cross-link the tissue through the polymer, depending on the specific embodiment. One of the methods described involves free radical polymerization of a first vinylic compound, which may include cross-linking through a second compound with at least two vinyl groups. Another method employs nucleophilic addition polymerization of two compounds, one of which may include PEG and hydrolytically degradable regions. The in-situ polymerization is believed to inhibit calcification, allowing for improved penetration of the polymer into the tissue. This innovative approach finds application in the treatment of porcine heart valve tissue, aiming to extend the useful life of the valves by preventing calcification.
Career Highlights
Anel Oostheysen is currently associated with Medtronic, Inc., a leading company in medical technology. His work at Medtronic focuses on advancing bioprosthetic solutions that can significantly improve patient outcomes. His dedication to research and development in this field has positioned him as a key player in the innovation of medical devices.
Collaborations
Anel has collaborated with esteemed colleagues such as Peter Paul Zilla and Deon Bezuidenhout. These partnerships have fostered a collaborative environment that enhances the development of innovative solutions in bioprosthetic tissue preparation.
Conclusion
Anel Oostheysen's contributions to the field of bioprosthetic tissue preparation exemplify the impact of innovation in medical technology. His patented methods and ongoing work at Medtronic highlight the importance of research in improving healthcare solutions.