Andrew Keller

Title: Innovations by Andrew Keller in Polypeptide Sequencing

Introduction

Andrew Keller is an accomplished inventor based in Seattle, WA. He has made significant contributions to the field of mass spectrometry, particularly in the quantification and sequencing of polypeptides. His innovative methods have the potential to advance research in various biological and chemical applications.

Latest Patents

Andrew Keller holds a patent for "Methods for quantification and de novo polypeptide sequencing by mass spectrometry." This invention provides a comprehensive method for determining the amino acid sequence of a parent polypeptide. The process involves obtaining mass spectra of differentially labeled polypeptide fragments, assigning mass and weighting characteristics to paired signals, and determining the differences in mass of the fragments. The method also includes constructing a graph from mass spectra to facilitate the identification of amino acid sequences.

Career Highlights

Keller is associated with the Institute for Systems Biology, where he applies his expertise in mass spectrometry to enhance our understanding of biological systems. His work has contributed to the development of innovative techniques that improve the accuracy and efficiency of polypeptide sequencing.

Collaborations

Andrew Keller collaborates with David R Goodlett, a fellow researcher in the field. Their combined efforts aim to push the boundaries of current methodologies in mass spectrometry and polypeptide analysis.

Conclusion

Andrew Keller's innovative work in polypeptide sequencing exemplifies the impact of scientific research on advancing technology in the life sciences. His contributions continue to shape the future of mass spectrometry and its applications.