Company Filing History:
Years Active: 2001
Title: Innovations of Andrew E Plymale in Microbial Reduction of Technetium
Introduction
Andrew E Plymale is an accomplished inventor based in Richland, WA (US). He has made significant contributions to the field of microbial methods, particularly in the reduction of technetium compounds. His innovative approach has implications for medical imaging, showcasing the intersection of microbiology and technology.
Latest Patents
Andrew E Plymale holds a patent for "Microbial methods of reducing technetium." This invention focuses on a method for microbial reduction of a technetium compound to form other compounds of value in medical imaging. The process involves combining the technetium compound with non-growing microbial cells that contain a technetium-reducing enzyme system, a stabilizing agent, and an electron donor in a saline solution under anaerobic conditions. The mixture is designed to be substantially free of inorganic technetium reducing agents and their reduction products. The resulting product is technetium of lower oxidation states, which can be partially controlled by the stabilizing agent. Notably, microorganisms such as strain Bry and strain CN-32 have been identified to contain the necessary enzyme systems for technetium reduction, capable of forming both mono nuclear and polynuclear reduced technetium species depending on the stabilizing agent used.
Career Highlights
Andrew E Plymale is associated with the Battelle Memorial Institute, where he has been able to apply his expertise in microbial technology. His work has contributed to advancements in the field, particularly in the context of environmental and medical applications.
Collaborations
Throughout his career, Andrew has collaborated with notable colleagues, including Raymond E Wildung and Thomas R Garland. These collaborations have further enriched his research and development efforts in microbial methods.
Conclusion
Andrew E Plymale's innovative work in microbial reduction of technetium represents a significant advancement in medical imaging technology. His contributions continue to influence the field and highlight the importance of interdisciplinary approaches in scientific research.