Roslindale, MA, United States of America

Andrew Curtis Kruse

USPTO Granted Patents = 11 

 

Average Co-Inventor Count = 4.9

ph-index = 5

Forward Citations = 111(Granted Patents)


Company Filing History:


Years Active: 2017-2023

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11 patents (USPTO):Explore Patents

Title: **Innovator Spotlight: Andrew Curtis Kruse**

Introduction

Andrew Curtis Kruse, a prolific inventor based in Roslindale, MA, has made significant contributions to the field of biotechnology with an impressive portfolio of 11 patents. His innovative work primarily focuses on enhancing immune responses and providing novel therapeutic solutions for various diseases.

Latest Patents

Among his latest innovations are groundbreaking patents that delve into immunotherapy techniques. The first, titled "High Affinity PD-1 Agents and Methods of Use," involves the development of high affinity PD-1 mimic polypeptides. These polypeptides consist of specific amino acid alterations compared to the wild-type PD-1 protein, significantly increasing their binding affinity for PD-L1. This innovation aims to modulate the activity of immune cells in mammals, offering promising routes for cancer treatment by blocking the interaction between PD-1 and its ligands.

Another notable patent is focused on "SIRP-Gamma Polypeptide Compositions and Treatment of Cancer." This invention presents decoy polypeptides, including SIRP-gamma, SIRP-beta, and SIRP-beta2, designed for immunotherapy, targeting a range of conditions such as cancer, anemia, and autoimmune diseases. These groundbreaking therapies are revolutionizing the approach to treating complex diseases and enhancing patient outcomes.

Career Highlights

Andrew's career has been marked by significant roles in reputable organizations, including his tenure at Leland Stanford Junior University and Ab Initio Biotherapeutics, Inc. His work has positioned him as a leader in the field of immunotherapy, where he continues to contribute to advanced research and development.

Collaborations

Throughout his career, Andrew has collaborated with notable experts, including Aaron Michael Ring and Aashish Manglik. These partnerships have enabled him to blend diverse insights and expertise, further enriching his innovative processes and enhancing the impact of his inventions.

Conclusion

Andrew Curtis Kruse stands out as an influential inventor in biotechnology, with a clear focus on immunology and therapeutic advancements. His extensive patent portfolio reflects his commitment to pushing the boundaries of science and improving health outcomes through innovation. With his continuous work, Andrew is likely to remain at the forefront of biotech innovation for years to come.

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