Company Filing History:
Years Active: 2008-2014
Title: Andrea Fleig: Innovator in Calcium Channel Research
Introduction
Andrea Fleig is a prominent inventor based in Honolulu, HI (US), known for her significant contributions to the field of cellular biology. With a total of five patents to her name, she has made remarkable strides in understanding calcium channels and their implications in cellular functions.
Latest Patents
Fleig's latest patents include groundbreaking work on the functional identification of proteins underlying Icrac activity in cells. This invention provides methods and compositions for determining the identity of CRACM homologs that are crucial for Icrac activity. Another notable patent focuses on methods of screening for LTRPC7 modulators. This invention relates to the identification and isolation of a novel family of ATP-regulated calcium transmembrane channel polypeptides, designated as 'LTRPC7'. These channels exhibit unique responses to intracellular ATP levels and are subject to inhibition by high levels of calcium and magnesium. The invention also outlines methods for utilizing LTRPC7 for binding, modulating its activity, and measuring LTRPC2 permeability.
Career Highlights
Andrea Fleig is currently affiliated with The Queen's Medical Center, where she continues her research and innovation in the field of calcium channels. Her work has been instrumental in advancing our understanding of cellular mechanisms and their potential therapeutic applications.
Collaborations
Fleig collaborates with Reinhold Penner, contributing to the advancement of research in their shared field of expertise.
Conclusion
Andrea Fleig's innovative work in calcium channel research has led to significant advancements in cellular biology. Her contributions through patents and collaborations continue to shape the future of this important scientific field.