The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2008
Filed:
May. 08, 2002
Applicants:
Reinhold Penner, Honolulu, HI (US);
Andrea Fleig, Honolulu, HI (US);
Inventors:
Reinhold Penner, Honolulu, HI (US);
Andrea Fleig, Honolulu, HI (US);
Assignee:
The Queen's Medical Center, Honolulu, HI (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates, in part, to methods useful in identifying molecules, that bind TRPM4, which modulate TRPM4ion channel activity, and/or which alter expression of TRPM4within cells. The TRPM4channels as described herein contain TRPM4polypeptides, which are in turn encoded by TRPM4nucleic acids. The ion channels described herein are preferably formed in HEK-293 cells from one or more novel TRPM4polypeptides, which exhibit one or more of the unique TRPM4properties described herein.