Andre A Asselin

Title: Innovations of Andre A Asselin

Introduction

Andre A Asselin is a notable inventor based in Mahwah, NJ (US). He has made significant contributions to the field of pharmaceuticals, particularly in the development of compounds that serve as NMDA antagonists. With a total of 3 patents to his name, Asselin's work has implications for anticonvulsant and neuroprotectant therapies.

Latest Patents

One of Asselin's latest patents involves a process for the preparation of the compound [2-((8,9)-dioxo-2,6-diazabicyclo[5.2.0]-non-1(7)-en-2-yl)ethyl]phosphonic acid. This compound is recognized for its potential as an NMDA antagonist, which is useful in situations involving excess release of excitatory amino acids. The process includes reacting 3-aminopropyl carbamic acid 1,1-dimethyl-ethyl ester with a dialkyl vinylphosphonate to yield N-[3-(t-butyloxycarbonyl-amino)propyl]-2-aminoethylphosphonic acid dialkyl ester in 80% yield. Further reactions lead to the formation of the final compound, showcasing Asselin's innovative approach to pharmaceutical chemistry.

Career Highlights

Asselin is currently associated with American Home Products Corporation, where he continues to apply his expertise in the development of pharmaceutical innovations. His work has been instrumental in advancing therapeutic options for various neurological conditions.

Collaborations

Throughout his career, Asselin has collaborated with notable colleagues, including Jean Schmid and William Alvin Kinney. These partnerships have contributed to the successful development of his patented inventions.

Conclusion

Andre A Asselin's contributions to the field of pharmaceuticals through his innovative patents highlight his role as a significant inventor. His work continues to influence the development of important therapeutic compounds.