An Soo Lee

Title: An Soo Lee: Innovator in Lipid Nanoparticle Technology

Introduction

An Soo Lee is a prominent inventor based in Seoul, South Korea. He has made significant contributions to the field of pharmaceutical technology, particularly in the development of lipid nanoparticles for drug delivery. His innovative work focuses on enhancing the stability and efficacy of nucleic acid drugs.

Latest Patents

An Soo Lee holds a patent for a pharmaceutical composition of lipid nanoparticles designed for delivering nucleic acid drugs. This composition includes a trehalose derivative and a novel structure-maintaining lipid compound. The lipid nanoparticles are engineered to stabilize nucleic acid drugs and improve their delivery in vivo. The nucleic acid drugs covered by this patent include mRNA-based vaccines, RNA for immune boosters, miRNA, siRNA, pDNA, and antisense ODN. The lipid components consist of a trehalose-based lipid, an ionizable lipid, a phospholipid, a PEG-lipid, and a structure-maintaining lipid. This innovative approach allows for the replacement of cholesterol with derivatives of lithocholic acid, glycyrrhetinic acid, or diosgenin, making the lipid nanoparticles versatile for use as vaccines or therapeutic agents.

Career Highlights

An Soo Lee is associated with SML Biopharm Co., Ltd., where he continues to advance his research in lipid nanoparticle technology. His work has garnered attention for its potential applications in the pharmaceutical industry, particularly in the development of effective drug delivery systems.

Collaborations

An Soo Lee collaborates with notable colleagues, including Eun Kyoung Bang and Gyo Chang Keum. Their combined expertise contributes to the innovative research and development efforts at SML Biopharm Co., Ltd.

Conclusion

An Soo Lee's contributions to lipid nanoparticle technology represent a significant advancement in the field of drug delivery. His innovative patent and ongoing research have the potential to impact the future of pharmaceutical therapies.