This inventor holds 3 USPTO granted patents. Top assignee: Chiron Corporation. Active years: 2000-2006.
Company Filing History:
Years Active: 2000-2006
Title: An D Tran: Innovator in Platelet-Derived Growth Factor Research
Introduction
An D Tran is a notable inventor based in Moraga, CA (US). He has made significant contributions to the field of biochemistry, particularly in the analysis and separation of platelet-derived growth factor (PDGF) proteins. With a total of 3 patents to his name, Tran's work has implications for pharmaceutical applications, especially in wound healing.
Latest Patents
Tran's latest patents focus on methods for improving the purification and quantification of PDGF proteins that exhibit structural heterogeneity. His innovative techniques involve the use of TSK sulfopropyl cation exchange chromatography and reverse phase high-performance liquid chromatography to achieve substantially pure isoforms of these proteins. Additionally, he has developed a reverse charged capillary zone electrophoresis method that allows for the quantification of these isoforms, which result from endoproteolytic post-translational modifications. The compositions he has invented include substantially purified isoforms of secreted PDGF proteins, specifically intact, single-clipped, and double-clipped isoforms of recombinant PDGF-BB. Furthermore, he has created pharmaceutical compositions that incorporate these purified recombinant PDGF isoforms, which are designed to promote wound healing.
Career Highlights
An D Tran is currently associated with Chiron Corporation, where he continues to advance his research in biochemistry and protein purification. His work has garnered attention for its potential applications in medical treatments and therapies.
Collaborations
Tran has collaborated with notable colleagues in his field, including Hugh Parker and Michael G Kunitani. Their combined expertise contributes to the innovative research and development of PDGF-related technologies.
Conclusion
An D Tran's contributions to the field of platelet-derived growth factor research highlight his role as a significant inventor in biochemistry. His innovative methods and compositions have the potential to impact wound healing therapies positively.