Company Filing History:
Years Active: 1998
Title: The Innovative Contributions of Amy M. Brunner in Biotechnology
Introduction: Amy M. Brunner is a notable inventor based in Seattle, Washington, recognized for her significant contributions to biotechnology, particularly in the realm of transforming growth factors. As a prominent figure at the Bristol-Myers Squibb Pharmaceutical Research Institute, she has made impactful advancements that enhance our understanding and application of biological processes.
Latest Patents: Amy M. Brunner holds a patent for the cloning and expression of simian transforming growth factor beta-1. This innovative work focuses on the recombinant expression of TGF-beta-1 in Chinese hamster ovary (CHO) cells, utilizing dihydrofolate reductase (dhfr) gene amplification. The expression plasmid, adapted from the pSV2 vectors, effectively expresses high levels of TGF-beta-1 and has implications for therapeutic applications. The results from her research demonstrate the ability to synthesize TGF-beta-1 proteins at significant levels, marking an important milestone in biopharmaceutical production.
Career Highlights: Throughout her career at Bristol-Myers Squibb, Amy M. Brunner has established herself as a key player in the field of pharmaceutical research. Her work with CHO cells and the pioneering techniques for producing TGF-beta-1 proteins have provided valuable insights into protein expression technology, thereby advancing the development of treatments in various medical fields.
Collaborations: Amy has collaborated with esteemed colleagues such as Anthony F. Purchio and Larry Gentry, leveraging their combined expertise to enhance the efficacy and depth of her research. These partnerships have allowed for multidisciplinary approaches to solving complex scientific problems and driving innovation in drug development.
Conclusion: Amy M. Brunner's innovative contributions to biotechnology and her pioneering work in the expression of transforming growth factors underscore her role as an influential inventor in the field. Her patent not only highlights her technical expertise but also reflects her commitment to improving biopharmaceutical advancements, paving the way for future discoveries and therapies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.