Amrinder Nain

Title: Amrinder Nain and Cell-Force-Based Intracellular Delivery

Introduction

Amrinder Nain is an inventor based in Blacksburg, Virginia, and is associated with Virginia Tech Intellectual Properties Inc. His work includes a patented approach to intracellular delivery that uses cell shape, mechanical forces, and electric fields to influence how compounds enter cells.

Latest Patents

Nain is named on 1 patent: “Method for Intracellular Delivery of Compounds Using Cell Force and Shape with Electric Fields.” The invention describes modifying cells’ shape, force, or structural integrity by applying an electric current while the cells are in contact with a polymeric nanofiber array. Adjusting the current’s direction and voltage can help control cell-membrane permeability and produce a desired cellular response. The disclosed method aims to improve cell survival during electroporation, enable delivery of molecules and drugs of different sizes, and increase transfection efficiency in rare primary cells.

Career Highlights

Nain’s patent reflects research at the intersection of cellular mechanics, nanofiber materials, and electrical stimulation. The method offers a way to tune membrane permeability while accounting for the physical properties of cells, with potential relevance to laboratory research and biomedical applications.

Collaborations

The patent is associated with Virginia Tech Intellectual Properties Inc., which supports the protection and management of intellectual property connected with Virginia Tech. The available information identifies the company but does not specify additional collaborators.

Conclusion

Amrinder Nain’s patented method combines cell mechanics, polymeric nanofiber arrays, and electric fields to advance intracellular delivery, with the goal of improving cell viability and delivery efficiency.