Amir Pesyan

Title: Amir Pesyan: Innovator in Nucleoside Manufacturing

Introduction

Amir Pesyan is a notable inventor based in Salt Lake City, UT (US). He has made significant contributions to the field of nucleoside manufacturing, holding 2 patents that showcase his innovative approaches.

Latest Patents

His latest patents focus on methods to manufacture 1,3-dioxolane nucleosides. These applications provide a process for preparing enantiomerically pure β-D-dioxolane nucleosides. In particular, a new synthesis of (−)-DAPD, suitable for large-scale development, is described. The invention outlines a process that includes several steps: preparing or obtaining an esterified 2,2-dialkoxy ethanol, cyclizing it with glycolic acid to obtain a 1,3-dioxolane lactone, resolving the lactone to obtain a substantially pure D- or L-lactone, selectively reducing and activating the chiral lactone, coupling it to an activated purine or pyrimidine base, and optionally purifying the nucleoside to achieve a substantially pure protected β-D- or β-L-1,3-dioxolane nucleoside.

Career Highlights

Amir Pesyan is affiliated with Emory University, where he continues to advance his research and innovations in the field of nucleosides. His work has the potential to impact various applications in pharmaceuticals and biotechnology.

Collaborations

He collaborates with esteemed colleagues, including Marcos Sznaidman and George R Painter, who contribute to his research endeavors.

Conclusion

Amir Pesyan's innovative work in nucleoside manufacturing exemplifies the importance of research and development in advancing scientific knowledge and applications. His contributions are paving the way for future advancements in the field.