Location History:
- Cambridge, MA (US) (2001 - 2006)
- Chapel Hill, NC (US) (2007)
Company Filing History:
Years Active: 2001-2007
Title: Innovations and Contributions of Alyson M Wilbanks
Introduction
Alyson M Wilbanks is a notable inventor based in Cambridge, MA (US). She has made significant contributions to the field of biochemistry and molecular biology, holding a total of 4 patents. Her work primarily focuses on G-protein coupled receptors and their therapeutic applications.
Latest Patents
One of her latest patents is titled "Nucleic acid encoding G-protein coupled receptor with modified DRY motif." This invention relates to modified G-protein coupled receptors (GPCRs) that have been altered to possess modified DRY motifs, resulting in constitutively desensitized GPCRs. These modified GPCRs are designed to localize to endocytic vesicles or endosomes in an agonist-independent manner. The invention also includes methods for screening compounds and sample solutions for GPCR activity using these modified receptors.
Another significant patent is "Antibodies for 'Bonzo' chemokine receptor and therapeutic uses thereof." This invention involves an antibody or antigen-binding fragment that binds to the CXC chemokine receptor Bonzo, blocking the binding of ligands such as SExCkine. The patent also describes methods for identifying agents that can bind to Bonzo and modulate its functions, which have potential applications in research, therapeutic, prophylactic, and diagnostic methods.
Career Highlights
Alyson has worked with prominent organizations such as Millennium Pharmaceuticals and Duke University. Her experience in these institutions has allowed her to collaborate with leading experts in her field and contribute to groundbreaking research.
Collaborations
Some of her notable coworkers include Michael J Briskin and Kristine E Murphy. Their collaborative efforts have further advanced the understanding and application of her inventions.
Conclusion
Alyson M Wilbanks is a distinguished inventor whose work in the field of G-protein coupled receptors has led to valuable patents and advancements in therapeutic applications. Her contributions continue to impact the scientific community and pave the way for future innovations.