Company Filing History:
Years Active: 1985-1989
Title: Innovations of Allan P Jarvis, Jr.
Introduction
Allan P Jarvis, Jr. is a notable inventor based in Newburyport, MA (US). He has made significant contributions to the field of biotechnology, particularly in the area of microencapsulation. With a total of five patents to his name, Jarvis has developed innovative processes that enhance the viability and functionality of encapsulated materials.
Latest Patents
One of his latest patents focuses on microencapsulation with polymers. This process allows for damage-free encapsulation of various core materials, including viable cells. The core material is suspended in an aqueous solution of a polymeric material containing cationic groups, such as aminated glucopolysaccharides like chitosan. A temporary matrix is formed by gelling droplets of the suspension with a divalent or multivalent anion. This matrix is then permanently cross-linked with a polymeric material containing plural anionic groups, such as polyaspartic or polyglutamic acid, to create a semipermeable membrane. The resulting microcapsules are non-sticky, do not clump, and support viable cell growth and proliferation.
Another significant patent involves the induction of immune response through immunization with encapsulated cells. Genetically modified cells, such as hybridomas that secrete antigenic substances, are encapsulated within membranes that allow the efflux of antigens while preventing the cells from escaping. When injected into an experimental animal, the antigens induce lymphocytes to produce specific antibodies. This innovative approach enables the harvesting of antibodies from the animal's circulatory system, facilitating the production of large quantities of monoclonal antibodies.
Career Highlights
Allan P Jarvis, Jr. is currently associated with Damon Biotech, Inc., where he continues to advance his research and development efforts. His work has garnered attention for its potential applications in medical and biotechnological fields.
Collaborations
Throughout his career, Jarvis has collaborated with notable colleagues, including Franklin Lim and George A Koch. These partnerships have contributed to the successful development of his innovative technologies.
Conclusion
Allan P Jarvis, Jr. is a distinguished inventor whose work in microencapsulation and immunization has the potential to revolutionize biotechnology. His contributions continue to impact the field positively, showcasing the importance of innovation in science and medicine.