Company Filing History:
Years Active: 2000-2001
Title: Innovations by Allan F. Horton
Introduction
Allan F. Horton is a notable inventor based in Miami, FL, who has made significant contributions to the field of cell analysis. With a total of three patents to his name, he has developed innovative methods that enhance the efficiency of analyzing biological samples. His work is particularly relevant in the context of flow cytometry and blood analysis.
Latest Patents
One of his latest patents is titled "Methods and compositions for rapid staining of nucleic acids in whole cells." This patent describes a rapid fluorescence staining method that facilitates flow cytometry analysis of reticulocytes. The method involves contacting cells with a cocktail containing a detergent, sphering agent, and a cell impermeable dye, such as TO-PRO-3, for about one minute. This innovative cocktail allows the dye to penetrate the cell membrane quickly, improving the staining process.
Another significant patent by Horton is "Method and apparatus for analyzing cells in a whole blood sample." This invention features a blood analyzing instrument that includes a single transducer capable of simultaneously measuring the DC volume, RF conductivity, light scattering, and fluorescence characteristics of blood cells as they pass through a cell-interrogation zone. The transducer is designed with an electro-optical flow cell that defines a cell-interrogation zone with specific dimensions, enhancing the accuracy of blood analysis.
Career Highlights
Allan F. Horton has been associated with Coulter International Corporation, where he has applied his expertise in developing advanced technologies for cell analysis. His work has contributed to the company's reputation as a leader in the field of biomedical instrumentation.
Collaborations
Throughout his career, Horton has collaborated with notable colleagues, including Kristie M. Gordon and James L. Wyatt. These collaborations have likely fostered an environment of innovation and shared knowledge, further enhancing the impact of their collective work.
Conclusion
Allan F. Horton is a distinguished inventor whose contributions to cell analysis have paved the way for advancements in biomedical research. His innovative patents reflect a commitment to improving the efficiency and accuracy of biological sample analysis.