This inventor holds 4 USPTO granted patents and 4 published patent applications, plus 1 CIPO patent and 1 EPO patent. Top assignee: The Wistar Institute. Active years: 2019-2026.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2019-2026
Title: Innovations of Alfredo Perales-Puchalt in Cancer Treatment
Introduction
Alfredo Perales-Puchalt is a notable inventor based in Philadelphia, PA (US). He has made significant contributions to the field of cancer treatment through his innovative research and patented technologies. With a total of 4 patents, his work focuses on developing methods and compositions that target cancer cells effectively.
Latest Patents
Perales-Puchalt's latest patents include groundbreaking methods and compositions for treating cancer. One of his key inventions involves a nucleic acid sequence that encodes a chimeric protein. This protein comprises a ligand that includes a naturally occurring or modified follicle stimulating hormone sequence, such as an FSHβ sequence, which binds to the human follicle stimulating hormone (FSH) receptor. The invention also links this ligand to either a nucleic acid sequence encoding an extracellular hinge domain, a transmembrane domain, a co-stimulatory signaling region, and a signaling endodomain, or a sequence that encodes a ligand binding to NKG2D. The vector containing this nucleic acid sequence, the chimeric proteins encoded, and modified T cells expressing the chimeric protein are all part of his innovative approach to treating FSHR-expressing cancers or tumor cells.
Career Highlights
Alfredo Perales-Puchalt is affiliated with The Wistar Institute, where he conducts his research and development work. His contributions to the field of cancer treatment have been recognized for their potential to improve therapeutic outcomes for patients.
Collaborations
One of his notable collaborators is Jose R Conejo-Garcia, with whom he has worked on various projects aimed at advancing cancer treatment methodologies.
Conclusion
Alfredo Perales-Puchalt's innovative work in cancer treatment exemplifies the impact of research and invention in the medical field. His patents reflect a commitment to developing effective therapies that could change the landscape of cancer treatment.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile