Company Filing History:
7 out of 7 
2 out of 805 
2 out of 40 
Years Active: 2016-2025
Title: Innovator Alexandra Leida Liana Lazetic: Pioneering Immunotherapy
Introduction
Alexandra Leida Liana Lazetic, a prominent inventor based in San Jose, CA, has made significant strides in the field of immunotherapy. With a total of 10 patents to her name, Lazetic has been at the forefront of research, developing innovative solutions that address critical health challenges, particularly in cancer treatment.
Latest Patents
Among her latest contributions are groundbreaking patents focused on CD19-directed chimeric antigen receptors (CAR) and the use of immune cell compositions in therapeutic applications. One notable patent details the creation of immune cell-based compositions that include natural killer (NK) cells equipped with humanized anti-CD19 CARs, designed to enhance both expression and cytotoxicity. This innovation significantly improves the persistence of these engineered immune cells in immunotherapy settings.
Another of her recent patents discusses immune cells comprising truncated NKG2D chimeric receptors. This composition relates to engineered NK cells that have an augmented ability to target cancerous and infectious disease-afflicted cells. By incorporating transmembrane and signaling domains into the NK cells, these innovations lead to effective cytotoxic interactions with targeted cells, paving the way for new treatment methodologies.
Career Highlights
Alexandra has held key positions in notable companies such as Nkarta, Inc. and the National University of Singapore. Her work has focused on enhancing the therapeutic potential of immune cells, providing actionable solutions that leverage the body’s own defenses against diseases.
Collaborations
Throughout her illustrious career, Lazetic has collaborated with esteemed colleagues, including James Barnaby Trager and Chao Guo. Their joint efforts in research and development have contributed significantly to the advancements in immunotherapy, positioning them as influential figures in the field.
Conclusion
Alexandra Leida Liana Lazetic exemplifies innovation within the biomedical sector, with a noteworthy portfolio of patents that highlights her dedication to enhancing immune therapies. Her pioneering research continues to influence the trajectory of immunotherapy, promising new avenues for treating complex diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.