Company Filing History:
Years Active: 1998-2014
Title: Innovations by Alexandra C. McPherron in Muscle Growth and Myostatin Modulation
Introduction
Alexandra C. McPherron, based in Baltimore, MD, has established herself as a prominent inventor in the field of biomedical research, holding an impressive total of 31 patents. Her groundbreaking work primarily focuses on the modulation of muscle growth and metabolic processes through innovative methods related to myostatin, a known regulator of muscle development.
Latest Patents
Among her latest patents, McPherron presents a significant innovation titled "Truncated Activin Type II Receptor and Methods of Use." This invention elaborates on a substantially purified growth differentiation factor (GDF) receptor, particularly the GDF-8 (myostatin) receptor, and includes functional peptide portions thereof. It also encompasses methodologies to modulate myostatin's effect on cells, aiming to ameliorate conditions linked with abnormal muscle or adipose tissue activity. Furthermore, her patent regarding "Polynucleotides Encoding Promyostatin Polypeptides" provides isolated polynucleotides associated with promyostatin peptides that can be pivotal in advanced genetic research and therapeutic applications.
Career Highlights
McPherron has made remarkable contributions through her affiliations with esteemed institutions such as The Johns Hopkins University School of Medicine and The Johns Hopkins University. Her work at these universities has not only enhanced academic research but has also opened avenues for potential clinical applications of her findings.
Collaborations
Collaboration has been an essential aspect of McPherron's career. She has worked alongside distinguished researchers such as Se-Jin Lee and Daniel S. Greenspan, contributing to advances in understanding muscle biology and metabolic regulation. These partnerships have further enriched her research and have played a critical role in driving forward scientific discovery in her field.
Conclusion
Alexandra C. McPherron's innovative contributions to the field of myostatin regulation and muscle growth present significant implications for developing therapeutic strategies against muscular disorders. Her extensive patent portfolio underscores her impact as a leading inventor in biomedical research, promising advancements that could transform health outcomes related to muscle and adipose tissue management.