This inventor holds 21 USPTO granted patents and 23 published patent applications and 4 EPO patents, primarily in Gene Editing Technology. Top assignees: Lifeedit Therapeutics, Inc., North Carolina State University. Active years: 2021-2026.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
18 out of 18 
3 out of 1,493 
Years Active: 2021-2026
Areas of Expertise:
Title: The Innovative Contributions of Alexandra Briner Crawley
Introduction
Alexandra Briner Crawley is a prominent inventor based in Cary, NC (US). She has made significant contributions to the field of biotechnology, particularly in the development of RNA-guided nucleases and DNA modifying enzymes. With a total of 21 patents to her name, Crawley is recognized for her innovative approaches to genetic editing and modification.
Latest Patents
Crawley's latest patents include groundbreaking work on RNA-guided nucleases and active fragments and variants thereof. These inventions provide compositions and methods for binding to a target sequence of interest, which can be utilized for cleaving or modifying that sequence. The compositions consist of RNA-guided nuclease (RGN) polypeptides, CRISPR RNAs, trans-activating CRISPR RNAs, guide RNAs, and nucleic acid molecules encoding these components. Additionally, she has developed systems for binding target sequences that incorporate RGN polypeptides and guide RNAs. Another significant patent involves novel deaminase polypeptides for targeted editing of nucleic acids, which includes fusion proteins that combine DNA-binding polypeptides with deaminases.
Career Highlights
Throughout her career, Crawley has worked with notable organizations such as Lifeedit Therapeutics, Inc. and North Carolina State University. Her work has been instrumental in advancing the field of genetic engineering, particularly in the application of CRISPR technology.
Collaborations
Crawley has collaborated with esteemed colleagues, including Tedd D Elich and Tyson D Bowen, contributing to her innovative research and development efforts.
Conclusion
Alexandra Briner Crawley stands out as a leading inventor in the biotechnology sector, with her patents paving the way for advancements in genetic editing technologies. Her contributions continue to influence the field and inspire future innovations.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile