Company Filing History:
Years Active: 2019-2024
Title: Innovations of Alexander Zhdanov in Oxygen Monitoring
Introduction
Alexander Zhdanov is a notable inventor based in Cork, Ireland. He has made significant contributions to the field of biomedical research, particularly in the area of oxygen monitoring in live mammalian cells. With a total of 2 patents, his work has the potential to advance our understanding of cellular metabolism and oxygen dynamics.
Latest Patents
Zhdanov's latest patents focus on innovative methods and probes for monitoring oxygen status in live mammalian cells. The first patent describes a method of determining oxygen concentration, metabolic activity, and the effects of test substances on live cell samples using a photoluminescence quenching technique. This method employs a photoluminescent probe that self-loads into the cells without the need for loading reagents. The probe consists of polymeric particles with an amphiphilic cationic polymer matrix, featuring a hydrophobic core and a hydrophilic positively charged surface. The second patent also centers on the use of photoluminescent probes for intracellular sensing of oxygen, particularly for assaying intracellular oxygen concentration. This probe includes a suspension of polymeric particles formed from an amphiphilic cationic co-polymer, which provides a hydrophobic core and a hydrophilic shell. The incorporation of a hydrophobic oxygen-sensitive photoluminescent dye allows for effective monitoring of oxygen levels within live cells.
Career Highlights
Alexander Zhdanov is affiliated with University College Cork, where he conducts his research and development activities. His work has garnered attention for its innovative approach to cellular monitoring and its implications for various biomedical applications.
Collaborations
Zhdanov collaborates with esteemed colleagues such as Dmitri Boris Papkovsky and Andreas Fercher. Their combined expertise enhances the research efforts in the field of oxygen monitoring and cellular analysis.
Conclusion
Alexander Zhdanov's contributions to the field of oxygen monitoring in live mammalian cells represent a significant advancement in biomedical research. His innovative methods and probes have the potential to improve our understanding of cellular processes and metabolic activity.