Company Filing History:
3 out of 40 
1 out of 4,126 
1 out of 19 Years Active: 2005-2015
Title: Innovations and Contributions of Alexander V Sokoloff
Introduction
Alexander V Sokoloff is a notable inventor based in Madison, WI (US). He has made significant contributions to the field of biotechnology, particularly in the development of peptide display systems. With a total of 5 patents, Sokoloff's work has advanced the understanding and application of targeted therapies.
Latest Patents
One of Sokoloff's latest patents is the "T7 phage peptide display system and uses thereof." This invention involves a bacteriophage T7 display vector designed for expressing and displaying an exogenous peptide. The display vector includes a polynucleotide encoding a bacteriophage T7 tail fiber protein p17, in which a hepatocyte-targeting determinant sequence is inactivated. Additionally, it contains a cloning site within the coding sequence for the tail fiber protein p17 or in a coding sequence for a capsid protein p10B. The invention also describes a host cell containing the display vector, a bacteriophage T7 particle with an exogenous peptide displayed, and a method for determining if a candidate peptide is a liver-targeting peptide.
Another significant patent involves compounds for targeting hepatocytes. This patent describes compounds that bind to and are internalized by hepatocytes. The association of these compounds with other molecules or complexes can be utilized to target these entities to hepatocytes in vivo or in vitro.
Career Highlights
Throughout his career, Sokoloff has worked with prominent organizations such as Mirus Bio Corporation and the Wisconsin Alumni Research Foundation. His work in these institutions has contributed to the advancement of biotechnological innovations.
Collaborations
Sokoloff has collaborated with notable individuals in his field, including Jon Asher Wolff and So Wong. These collaborations have further enhanced his research and development efforts.
Conclusion
Alexander V Sokoloff's contributions to biotechnology through his innovative patents and collaborations have significantly impacted the field. His work continues to pave the way for advancements in targeted therapies and peptide display systems.