This inventor holds 1 USPTO granted patent and 1 published patent application. Top assignees: Quadrant Biosciences Inc., The Penn State Research Foundation, The State University of New York. Active years: 2022.
Company Filing History:
1 out of 3 
1 out of 1,338 
1 out of 2,043 
Years Active: 2022
Title: The Innovative Contributions of Alexander Rajan
Introduction
Alexander Rajan is a notable inventor based in Syracuse, NY (US). He has made significant strides in the field of medical diagnostics, particularly concerning autism spectrum disorder (ASD). His work focuses on utilizing advanced methodologies to differentiate between individuals with ASD and those who are typically developing or developmentally delayed.
Latest Patents
Rajan holds a patent titled "Analysis of Autism Spectrum Disorder." This innovative application provides methods to differentiate between subjects with autism spectrum disorder and typically developing or developmentally delayed subjects using miRNA and/or microbiome levels detected in saliva samples. The method can be instrumental in monitoring the progress of ASD and guiding its treatment. Techniques such as RNA-seq and qPCR are employed to determine the counts and abundance of miRNA or microbiomes. The data is refined by normalization to expression levels or abundance of time-invariant miRNAs and/or microbial RNAs to control for sample collection timing or circadian fluctuations. Furthermore, multivariate logistic regression and nonlinear classification techniques are utilized to select a panel of miRNAs and microbiomes that accurately differentiate between subjects with ASD, DD, and TD in individuals with an unknown ASD status. These panels may eventually be developed into an RNA assay kit.
Career Highlights
Throughout his career, Alexander Rajan has worked with prominent organizations, including Quadrant Biosciences Inc. and the State University of New York. His contributions to the field of autism research have been recognized for their potential impact on diagnosis and treatment.
Collaborations
Rajan has collaborated with esteemed colleagues such as Steven D. Hicks and Frank A. Middleton. Their combined expertise has further advanced the research and development of innovative solutions in the field of autism spectrum disorder.
Conclusion
Alexander Rajan's work exemplifies the intersection of innovation and medical research. His patent on the analysis of autism spectrum disorder showcases his commitment to improving diagnostic methods and treatment options for individuals affected by ASD. His contributions are paving the way for future advancements in this critical area of healthcare.