Alexander McIntyre Rowe

Title: Alexander McIntyre Rowe: Innovator in T Cell Receptor Cloning

Introduction

Alexander McIntyre Rowe is a notable inventor based in Pittsburgh, PA (US). He has made significant contributions to the field of immunology, particularly in the area of T cell receptor (TCR) cloning. His innovative work has the potential to advance therapeutic strategies in various diseases.

Latest Patents

Rowe holds a patent for "Methods and materials for cloning functional T cell receptors from single T cells." This patent outlines methods and materials involved in cloning functional TCRs from single T cells. It includes techniques for obtaining nucleic acid encoding a TCR from a single T cell and arranging that nucleic acid to form vectors designed to express a TCR. The patent also describes kits for obtaining nucleic acid encoding a TCR and methods for making such kits. Additionally, it provides collections of nucleic acid primers designed to amplify the entire coding sequence of both variable regions for each expressed V segment for functional αβ or γδ TCRs of a particular mammalian species.

Career Highlights

Rowe is affiliated with the University of Pittsburgh, where he conducts research and develops innovative solutions in the field of immunology. His work has garnered attention for its potential applications in medical therapies.

Collaborations

Rowe has collaborated with esteemed colleagues such as Mark Shlomchik and Adriana Turqueti Neves. These collaborations have contributed to the advancement of research in T cell receptor cloning and its applications.

Conclusion

Alexander McIntyre Rowe is a pioneering inventor whose work in T cell receptor cloning is paving the way for future advancements in immunotherapy. His contributions are vital to the ongoing research in this important field.