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For the Inventor, By the Inventor

Portage, MI, United States of America

Alexander D Argoudelis

USPTO Granted Patents = 15

Average Co-Inventor Count = 2.4

ph-index = 5

Forward Citations = 67(Granted Patents)


Company Filing History:

goldMedal15 out of 2,170 
 
The Upjohn Co.
 patents

Years Active: 1976-1985

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15 patents (USPTO):Explore Patents
1. 4540661 - Composition of matter and process (1985-09-10),
2. 4505895 - Antibiotic 273.sub.a1 (1985-03-19),
3. 4464466 - Process of producing lincomycin nucleotides (1984-08-07),
4. 4430495 - Process for preparing lincomycin and clindamycin ribonucleotides (1984-02-07),
5. 4383109 - Lincomycin nucleotides (1983-05-10),
6. 4368193 - Process for treating malaria (1983-01-11),
7. 4335108 - Paulomycin A and B and preparation thereof (1982-06-15),
8. 4259450 - Antibiotic acanthomycin and process for preparing (1981-03-31),
9. 4091201 - Process for recovering antibiotics U-50,147 and U-51,738 (1978-05-23),
10. 4029548 - Process for producing antibiotics U-50,147 and U-51,738 (1977-06-14),
11. 4001267 - Feldamycic acid (1977-01-04),
12. 3998698 - Process for producing antibiotic U-51,640 (1976-12-21),
13. 3993748 - Antibiotic U-47,929 and its preparation (1976-11-23),
14. 3988314 - Compound U-50,228, derivatives thereof, and processes for preparation (1976-10-26),
15. 3969515 - Antibiotic U-48,266 (1976-07-13),

Title: The Innovative Contributions of Alexander D Argoudelis

Introduction

Alexander D Argoudelis is a notable inventor based in Portage, MI (US). He has made significant contributions to the field of antibiotics, holding a total of 15 patents. His work focuses on the development of novel antibiotics that demonstrate efficacy against various bacterial strains.

Latest Patents

Among his latest patents is the composition of matter and process for producing Antibiotic U-66,026. This antibiotic is generated through fermentation under controlled conditions using the microorganism Alcaligenes sp., NRRL B-15269. Enhanced fermentation titers of U-66,026 are achieved when Alcaligenes sp., NRRL B-15269, is cultivated in a mixture with Streptomyces plicatus strain 395, NRRL 15273. Antibiotic U-66,026 exhibits antifungal activity, making it a valuable addition to antibiotic therapies. Another significant patent is for Antibiotic 273.sub.a1, which includes novel antibiotics designated 273a.sub.1.spsb..alpha. and 273a.sub.1.spsb..beta. These antibiotics can be produced through fermentation using Streptomyces paulus, strain 273, NRRL 12251, and are effective against various Gram-positive bacteria while being soluble in aqueous solutions.

Career Highlights

Alexander D Argoudelis has had a distinguished career at The Upjohn Company, where he has been instrumental in advancing antibiotic research. His innovative approaches have led to the development of antibiotics that address critical health challenges.

Collaborations

Throughout his career, Argoudelis has collaborated with notable colleagues, including Fritz Reusser and Vincent P Marshall. These partnerships have fostered a collaborative environment that enhances the research and development of new antibiotics.

Conclusion

Alexander D Argoudelis stands out as a prominent inventor in the field of antibiotics, with a strong portfolio of patents that contribute to medical advancements. His work continues to impact the healthcare industry positively.

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