Alexander A Shishkin

Title: Alexander A. Shishkin: Innovator in RNA Sequencing Technology

Introduction

Alexander A. Shishkin is a prominent inventor based in Pasadena, CA (US). He has made significant contributions to the field of RNA sequencing, holding 2 patents that showcase his innovative approaches. His work focuses on developing methods that enhance the efficiency and accuracy of RNA sequencing.

Latest Patents

One of his latest patents is related to massively multiplexed RNA sequencing. This invention introduces a universal strand-specific protocol for the sequencing preparation of all classes of RNA. The protocol allows for the simultaneous sequencing of dozens to thousands of samples. Specifically, the method involves providing samples of RNA from multiple sources, labeling the RNA with a unique nucleic acid adaptor, reverse transcribing the RNA to create single-stranded DNA, amplifying the DNA, and sequencing the amplification products. This process ensures that target RNA from various sources can be sequenced while maintaining source identification.

Career Highlights

Throughout his career, Alexander A. Shishkin has worked with esteemed organizations such as the Broad Institute, Inc. and the Massachusetts Institute of Technology. His experience in these institutions has contributed to his expertise in RNA research and sequencing technologies.

Collaborations

Some of his notable coworkers include Mitchell Guttman and Christine F. Surka. Their collaborative efforts have further advanced the field of RNA sequencing and contributed to the success of their projects.

Conclusion

Alexander A. Shishkin is a key figure in the development of innovative RNA sequencing technologies. His patents and collaborations reflect his commitment to advancing scientific research in this vital area.