Alexander A Greenfield

Title: Alexander A Greenfield: Innovator in Immunosuppressive Compounds

Introduction

Alexander A Greenfield is a notable inventor based in Princeton Junction, NJ (US). He has made significant contributions to the field of immunosuppressive and anti-inflammatory compounds, holding a total of 3 patents. His work has implications for various medical treatments, particularly in transplantation and autoimmune diseases.

Latest Patents

One of Greenfield's latest patents involves alkylated rapamycin derivatives. This invention relates to compounds that possess immunosuppressive and/or anti-tumor and/or anti-inflammatory activity in vivo and/or inhibit thymocyte proliferation in vitro. These compounds are useful in the treatment of transplantation rejection, autoimmune diseases such as lupus, rheumatoid arthritis, diabetes mellitus, multiple sclerosis, and Candida albicans infections. They also play a role in treating diseases of inflammation.

Another significant patent from Greenfield includes carbazole inhibitors of Cox-2. This invention provides compounds with a specific structure that can be utilized in various therapeutic applications. The compounds are designed to have multiple functional groups, allowing for a wide range of biological activities.

Career Highlights

Greenfield is associated with American Home Products Corporation, where he has been able to apply his innovative ideas in a corporate setting. His work has contributed to advancements in pharmaceutical research and development.

Collaborations

Throughout his career, Greenfield has collaborated with notable colleagues, including Thomas Joseph Caggiano and Craig E Caufield. These collaborations have likely enhanced the scope and impact of his inventions.

Conclusion

Alexander A Greenfield is a prominent inventor whose work in immunosuppressive compounds has the potential to significantly impact medical treatments. His contributions continue to advance the field of pharmaceuticals and improve patient outcomes.