Alex De Gasparo

Title: **Alex De Gasparo: Innovator in Calcium Deficient Hydroxyapatite Granules**

Introduction

Alex De Gasparo, an inventive spirit from Biel, Switzerland, has made significant contributions to the field of materials science with a focus on calcium deficient hydroxyapatite granules. With a portfolio of two patents to his name, he is recognized for his innovative methods that are poised to advance the application of biologically active substances.

Latest Patents

Among his latest patents, the method for producing porous calcium deficient hydroxyapatite granules stands out as a noteworthy advancement. This method involves several steps:

(a) Subjecting granules of calcium sulfate anhydrous (CSA), calcium sulfate dihydrate (CSD), or calcium sulfate hemihydrate (CSH) to a first incubation in an alkaline aqueous solution with a pH of less than 10, containing phosphate ions (PO3−);

(b) A second incubation in an alkaline aqueous solution with a pH of more than 10, optionally containing PO3−;

(c) Filtering and drying the obtained porous granules;

(d) Ensuring that the total amount of phosphate ions used is at least as large as the amount of sulfate ions (SO4−) from the initial granules. The resulting porous granules are particularly beneficial as carriers for biologically active substances, especially proteins.

Career Highlights

Alex's professional journey includes working with renowned organizations such as Bioventus, LLC and Mathys Ag Bettlach. His experience at these companies has provided him with valuable insights into the practical applications of his inventions in real-world settings.

Collaborations

Throughout his career, Alex has collaborated with fellow professionals, including Noemie Van Garderen and Marc Bohner. These partnerships have likely enriched his research and driven innovative solutions in the materials science domain.

Conclusion

Alex De Gasparo's contributions to the development of porous calcium deficient hydroxyapatite granules demonstrate his commitment to innovation in biomaterials. With a solid foundation of patents and collaborative efforts, he continues to pave the way for advancements that bridge the gap between science and practical application.