Company Filing History:
1 out of 163 
1 out of 14 Years Active: 2009
Title: Alessandro Rustici: Innovator in Polymyxin B Analog Research
Introduction
Alessandro Rustici, located in Siena, Italy, is an accomplished inventor known for his contributions to the field of biochemistry, particularly in the area of antimicrobial research. With a focus on developing innovative solutions for combating bacterial infections, he holds a significant patent that reflects his expertise and dedication to science.
Latest Patents
Rustici's patent, titled "Polymyxin B analogs for LPS detoxification," demonstrates his innovative approach to addressing the challenges posed by Gram-negative bacteria. This invention relates to SAEP II peptide dimers that mimic polymyxin B, showcasing their ability to non-covalently bind to lipopolysaccharide (LPS) with a high affinity, thereby detoxifying it. The dimeric structure is stabilized by disulfide bonds between cysteine residues, and the peptide sequences consist of cationic and hydrophobic amino acid residues, not exceeding 17 in length. These dimers are particularly useful in treating or preventing septic shock and related disorders caused by infections from Gram-negative bacteria. The invention also includes LPS-peptide complexes which can serve as vaccinal agents against such infections.
Career Highlights
Throughout his career, Alessandro Rustici has worked with reputable companies like Sanofi Pasteur Inc. and Biosynth S.r.l., where he has applied his skills in research and development. His work in these esteemed organizations underscores his capability and commitment to advancing medical science and innovation.
Collaborations
In his journey of innovation, Rustici collaborated with esteemed colleagues such as Massimo Porro and Massimo Velucchi. These partnerships reflect a collaborative spirit that is often essential in the pursuit of groundbreaking research and inventions.
Conclusion
Alessandro Rustici's contributions to the field of biochemistry and his patent for Polymyxin B analogs highlight his innovative mindset and dedication to solving pressing health challenges. His achievements not only advance scientific understanding but also pave the way for potential treatments and preventative measures against serious bacterial infections, solidifying his position as a notable inventor in modern medicine.