Company Filing History:
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1 out of 3 Years Active: 2014
Title: Alessandro Ascione: Innovator in Antibody Derivatives
Introduction
Alessandro Ascione, an esteemed inventor based in Rome, Italy, has made significant contributions to the field of biomedicine with his groundbreaking inventions. With a total of two patents to his name, his work primarily focuses on the development of stabilized antibody derivatives, which have potential applications in the diagnosis and treatment of cancer.
Latest Patents
Alessandro Ascione’s latest patents include innovative solutions in antibody technology. The first patent describes an anti-CEA single-chain variable fragment (scFv) that possesses an uncleaved Pel B leader sequence, providing surprising stability and high specificity for carcinoembryonic antigen (CEA) and CEACAM1. This stability and specificity are crucial for developing targeted therapies. His second patent presents a scFv that can recognize an epitope of the extracellular domain of the CD99 human protein. This single-chain variable fragment has shown promise in selectively binding to CD99 expressed on Ewing sarcoma cells, offering potential for diagnosis and therapeutic strategies in treating this type of cancer.
Career Highlights
Throughout his career, Alessandro has contributed to various esteemed organizations, such as the Istituto Superiore Di Sanità and Diatheva S.r.l. His work at these institutions has allowed him to refine his skills and focus on innovative biotechnological solutions. Alessandro's expertise in antibody engineering continues to pave the way for medical advancements.
Collaborations
Alessandro has collaborated with notable colleagues, including Maurizio Cianfriglia and Michela Flego. Together, they have worked on significant projects that harness their collective knowledge and expertise in the field of biotechnology and biomedical research, further enhancing the impact of their inventions.
Conclusion
Alessandro Ascione stands out as an influential inventor in the realm of antibody derivatives. His patents not only highlight his innovative thinking but also illustrate the potential for his work to improve diagnostic and therapeutic strategies in medicine. With a strong foundation built on collaboration and dedication, Alessandro continues to contribute significantly to the fight against cancer through advancements in antibody technology.