Location History:
- Massa, IT (2015)
- Gallicano, IT (2023)
Company Filing History:
Years Active: 2015-2023
Title: Alessandra Lazzarotti: Innovator in Plasma Purification Technologies
Introduction
Alessandra Lazzarotti is a notable inventor based in Massa, Italy. She has made significant contributions to the field of biopharmaceuticals, particularly in the purification of proteins from human plasma. With a total of 2 patents, her work focuses on developing processes that enhance the safety and efficacy of therapeutic products derived from human plasma.
Latest Patents
Lazzarotti's latest patents include a process for plasminogen purification starting from human plasma. This innovative method involves several key stages, including virus inactivation through a solvent/detergent mixture, a single affinity chromatographic step, and a virus removal nanofiltration step. The process is designed to be scalable to industrial levels and produces a functional and intact finished product suitable for treating genetic plasminogen deficiency.
Another significant patent is for the industrial-scale purification of gamma globulins from human plasma. This invention outlines a novel process that includes two chromatographic steps: cation exchange capture chromatography followed by polishing anion exchange chromatography. This method ensures a highly purified end product with no aggregates and high yields, while also incorporating a virus inactivation step and a virus removal step through nanofiltration.
Career Highlights
Alessandra Lazzarotti is currently employed at Kedrion S.p.a., a company known for its expertise in the production of plasma-derived therapies. Her work at Kedrion has allowed her to apply her innovative processes in a practical setting, contributing to advancements in the biopharmaceutical industry.
Collaborations
Throughout her career, Lazzarotti has collaborated with esteemed colleagues, including Claudio Farina and Claudia Nardini. These partnerships have fostered a collaborative environment that enhances the development of new technologies in plasma purification.
Conclusion
Alessandra Lazzarotti's contributions to the field of plasma purification are noteworthy and impactful. Her innovative processes not only advance the safety and efficacy of therapeutic products but also demonstrate her commitment to improving human health through scientific innovation.