Location History:
- Brookline, MA (US) (2012 - 2013)
- Brighton, MA (US) (2006 - 2017)
- Boston, MA (US) (2002 - 2018)
Company Filing History:
5 out of 2,893 
4 out of 8,393 
3 out of 2,123 
Years Active: 2002-2018
Title: Aleksey G Kazantsev: Innovator in Therapeutic Compounds
Introduction
Aleksey G Kazantsev is a prominent inventor based in Boston, MA (US). He has made significant contributions to the field of therapeutic compounds, holding a total of 9 patents. His work focuses on innovative solutions for treating complex diseases, including neurodegenerative disorders.
Latest Patents
Kazantsev's latest patents include groundbreaking research on benzamide compounds and related methods of use. These compounds are designed for selective inhibition of the SIRT2 enzyme and have therapeutic applications in treating Huntington's disease. Another notable patent involves small molecule activators of the NRF2 pathway. This disclosure relates to compounds that act as high-affinity reversible bindings for the NRF2 inhibitor, KEAP1. These compounds can repress the expression of inflammatory markers and reduce levels of TNFa, providing neuroprotective anti-inflammatory effects in the central nervous system. Such innovations are crucial for addressing diseases like Huntington's disease, Parkinson's disease, Alzheimer's disease, inflammation, and cancer.
Career Highlights
Kazantsev has worked with esteemed organizations, including The General Hospital Corporation and the Massachusetts Institute of Technology. His career is marked by a commitment to advancing medical science through innovative research and development.
Collaborations
Throughout his career, Kazantsev has collaborated with notable colleagues, including David E Housman and Richard B Silverman. These partnerships have contributed to the success of his research and the development of his patented compounds.
Conclusion
Aleksey G Kazantsev stands out as a key figure in the field of therapeutic innovations. His contributions through patents and collaborations continue to pave the way for advancements in medical treatments.