Company Filing History:
Years Active: 2020
Title: Alberto Minassi: Innovator in Triterpenoid Derivatives
Introduction
Alberto Minassi is a notable inventor based in Novara, Italy. He has made significant contributions to the field of biochemistry, particularly through his innovative work on hydroxamate triterpenoid derivatives. His research focuses on the therapeutic potential of these compounds in various medical conditions.
Latest Patents
Alberto Minassi holds a patent for "Hydroxamate triterpenoid derivatives." This patent describes triterpenoid derivatives and compositions that exhibit the ability to bind PHD2, stabilize HIF-1α and HIF-2α proteins, and activate the HIF pathway in different cell types. These compounds have shown promising results in inducing angiogenesis in human endothelial vascular cells, demonstrating neuroprotective activity both in vitro and in vivo, and exhibiting antidiabetic properties. Additionally, they can reduce lipid levels in vivo and increase plasma levels of Erythropoietin. The derivatives act selectively without inducing Nrf2 activation, NF-κB inhibition, STAT3 inhibition, or TGR5 activation, which are common activities of natural triterpenoid precursors. These triterpenoid derivatives are particularly useful in treating conditions responsive to HIF activation, such as stroke, cerebral palsy, traumatic injuries, neurodegenerative diseases, inflammatory bowel disease, myocardial ischemia-reperfusion injury, acute lung injury, diabetic and chronic wounds, organ transplantation, acute kidney injury, and arterial diseases. He has 1 patent to his name.
Career Highlights
Alberto Minassi is currently associated with Vivacell Biotechnology España, S.L., where he continues to advance his research in biochemistry and pharmacology. His work has the potential to impact various therapeutic areas significantly.
Collaborations
He collaborates with esteemed colleagues, including Eduardo Munoz Blanco and Maria Luz Bellido Cabello De Alba, contributing to a dynamic research environment that fosters innovation.
Conclusion
Alberto Minassi's contributions to the field of triterpenoid derivatives highlight his role as an influential inventor in biochemistry. His innovative research holds promise for developing new treatments for various medical conditions.