Albert Loffet

Title: Albert Loffet: Innovator in Chiral Chemistry

Introduction

Albert Loffet is a notable inventor based in Paris, France. He has made significant contributions to the field of chiral chemistry, particularly through his innovative processes. His work focuses on the preparation of specific chemical compounds that are essential in various applications.

Latest Patents

Loffet holds a patent for a process related to the stereospecific preparation of 5-(1-hydroxy-2-urethanethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione derivatives. This invention involves a method where an N-urethane-protected α-amino acid N-carboxy-anhydride is reacted with Meldrum's acid in an inert organic solvent medium, facilitated by a tertiary amine. This process is significant as it conserves the chirality of the starting material, simplifying the synthesis of 4-amino-3-hydroxy acids and their derivatives via the tetramic acid route. Loffet's patent is a testament to his expertise and innovative approach in the field.

Career Highlights

Albert Loffet is associated with Propeptide, a company that focuses on peptide synthesis and related technologies. His work at Propeptide has allowed him to explore and develop new methodologies in chemical synthesis. Loffet's contributions have been recognized within the scientific community, showcasing his commitment to advancing chiral chemistry.

Collaborations

Loffet has collaborated with notable colleagues such as Jean-Alain Fehrentz and Jean Martinez. These collaborations have further enriched his research and development efforts, leading to advancements in their shared field of expertise.

Conclusion

Albert Loffet is a distinguished inventor whose work in chiral chemistry has led to innovative processes that enhance the synthesis of important chemical compounds. His contributions continue to impact the field positively, demonstrating the importance of innovation in scientific research.