Company Filing History:
Years Active: 1992-1995
Title: Albert H. Soloway: Innovator in Boron Neutron Capture Therapy
Introduction
Albert H. Soloway is a notable inventor based in Worthington, OH (US). He has made significant contributions to the field of boron neutron capture therapy through his innovative research and inventions. With a total of 2 patents, Soloway's work focuses on the development of novel boron-containing nucleosides and amino acids.
Latest Patents
Soloway's latest patents include "Carboranyl uridines and their use in boron neutron capture therapy." This invention relates to novel boron-containing nucleosides and amino acids that can utilize the enzymatic systems in tumor cells for incorporating such boron-containing structures into nucleic acids and proteins. The subsequent use of boron neutron capture therapy provides a method for treating tumor cells. Another significant patent is "2' and 3' Carboranyl uridines and their diethyl ether adducts." This patent discloses a process for preparing carboranyl uridine nucleoside compounds and their diethyl ether adducts, which exhibit a tenfold increase in boron content over prior art boron-containing nucleoside compounds. These compounds demonstrate enhanced lipophilicity and hydrophilic properties, enabling solvation in aqueous media for incorporation in methods for boron neutron capture therapy in mammalian tumor cells.
Career Highlights
Albert H. Soloway is affiliated with The Ohio State University, where he continues to advance his research in the field of cancer treatment. His work has garnered attention for its potential to improve therapeutic outcomes for patients with tumors.
Collaborations
Throughout his career, Soloway has collaborated with esteemed colleagues, including Rolf F. Barth and Abul K. Anisuzzaman. These collaborations have contributed to the advancement of research in boron neutron capture therapy.
Conclusion
Albert H. Soloway's innovative contributions to boron neutron capture therapy highlight his role as a leading inventor in the field. His patents reflect a commitment to improving cancer treatment methodologies, showcasing the importance of research and innovation in medical science.