Company Filing History:
Years Active: 2024
Title: Albert Gacerez: Innovator in Immunotherapy
Introduction
Albert Gacerez is a notable inventor based in Lebanon, NH (US). He has made significant contributions to the field of immunotherapy through his innovative research and patents. His work focuses on the development of nucleic acid constructs that enhance the efficacy of immune cells in treating various diseases.
Latest Patents
Gacerez holds a patent titled "Nucleic acid constructs for co-expression of chimeric antigen receptor and transcription factor, cells containing and therapeutic use thereof." This patent describes nucleic acid constructs, vectors, and recombinant cells that harbor these constructs. The constructs include genes encoding a chimeric antigen receptor (CAR) and/or one or more transcription factors, which may be mutated. The transcription factors mentioned in the patent are those that mediate proinflammatory cytokine expression, such as T-bet, STAT1, or STAT4. The patent also outlines methods for co-expressing the CAR and transcription factor in human or non-human immune cells, particularly human T cells. Furthermore, it details methods for utilizing these cells in immunotherapy to treat cancer, infections, autoimmune diseases, allergies, or inflammatory conditions.
Career Highlights
Albert Gacerez is affiliated with Dartmouth College, where he conducts his research and collaborates with other experts in the field. His work has garnered attention for its potential applications in therapeutic settings, particularly in enhancing the immune response against various diseases.
Collaborations
Gacerez collaborates with Charles L Sentman, who is also involved in research related to immunotherapy and cellular engineering. Their partnership aims to advance the understanding and application of CAR-T cell therapies.
Conclusion
Albert Gacerez is a pioneering inventor whose work in nucleic acid constructs has the potential to revolutionize immunotherapy. His contributions to the field are significant, and his ongoing research continues to inspire advancements in medical science.