Company Filing History:
Years Active: 1986
Title: **Alan J. Schroit: Innovator in Lipid Tracing Techniques**
Introduction
Alan J. Schroit, based in Gaithersburg, MD, is an esteemed inventor known for his significant contributions to the field of lipid labeling techniques. With a focus on creating highly specific radioactivity lipids, he has made noteworthy advancements that enhance the accuracy of various biological assays.
Latest Patents
Schroit holds a patent for a unique phospholipid known as N-(3-(3-.sup.125 iodo, 4-hydroxybenzyl)propionyl)phosphatidylethanolamine, commonly referred to as [.sup.125 I-phenylpropionyl-PE]. This nonexchangeable iodinated lipid exhibits high specific radioactivity and is synthesized through a method involving the acylation of phosphatidylethanolamine. The innovation also includes the synthesis of additional iodinated lipids using cyclic organic acids and the purification process via thin-layer chromatography. The resulting iodinated lipids are instrumental as accurate tracers in liposome-based assays, allowing for enhanced sensitivity that surpasses traditional lipid-labeling methods.
Career Highlights
Throughout his career, Alan Schroit has made significant strides in the realm of biochemical research. His work at Litton Bionetics, Inc. has placed him at the forefront of lipid research, where he has applied his expertise to develop advanced methodologies for lipid labeling. His innovative approaches have had a profound impact on the field, facilitating more precise measurements in a range of biological research applications.
Collaborations
During his time at Litton Bionetics, Inc., Schroit has collaborated closely with his coworker Isaiah J. Fidler. Their partnership has fostered an environment of innovation, enabling them to explore new avenues in lipid research and develop groundbreaking techniques that benefit the scientific community.
Conclusion
Alan J. Schroit has established himself as a notable inventor in the field of biochemistry, particularly through his patent for iodinated lipids and their applications in research. His dedication to advancing lipid tracing technology not only enhances scientific understanding but also paves the way for future innovations in biochemical assays.