Alan Howard Lyons

Title: Alan Howard Lyons: Innovator in Antibody Technology

Introduction

Alan Howard Lyons is a notable inventor based in Maidenhead, GB. He has made significant contributions to the field of biotechnology, particularly in the development of humanized antibody molecules. With a total of 2 patents, his work has had a substantial impact on medical diagnostics and therapies.

Latest Patents

One of his latest patents focuses on Anti-HMFG antibodies and processes for their production. This patent describes humanized antibody molecules (HAMs) that have specificity for human milk fat globule. The antigen binding site of these HAMs includes at least one complementarity determining region (CDR) derived from the mouse monoclonal antibody CTMO1, while the remaining parts are derived from human immunoglobulin. These HAMs can be classified as chimeric humanized antibodies or CDR-grafted humanized antibodies, and they are preferably produced using recombinant DNA techniques. The applications of these HAMs are significant, as they are useful for in vivo diagnosis and therapy.

Career Highlights

Throughout his career, Alan has worked with prominent companies in the biotechnology sector, including Celltech Limited and Celltech R&D Limited. His experience in these organizations has allowed him to refine his expertise in antibody technology and contribute to innovative solutions in the field.

Collaborations

Alan has collaborated with several notable individuals in his field, including John Robert Adair and Raymond John Owens. These collaborations have further enhanced his research and development efforts.

Conclusion

Alan Howard Lyons is a distinguished inventor whose work in humanized antibodies has paved the way for advancements in medical diagnostics and therapies. His contributions continue to influence the biotechnology landscape significantly.