Tyne and Wear, United Kingdom

Alan H Calvert


Average Co-Inventor Count = 5.5

ph-index = 7

Forward Citations = 124(Granted Patents)


Company Filing History:


Years Active: 1998-2004

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9 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Alan H. Calvert

Introduction

Alan H. Calvert is a distinguished inventor based in Tyne and Wear, Great Britain. With a remarkable portfolio of nine patents, his work primarily focuses on developing therapeutic compounds, particularly in the field of oncology.

Latest Patents

Among his notable inventions is a patent for cyclin-dependent kinase inhibitors. This range of pyrimidine derivatives acts as inhibitors of cyclin-dependent kinases (CDKs), offering potential therapeutic applications for the treatment of tumors and other cell proliferation disorders. The compounds showcase a unique binding mechanism to CDK molecules, differing from known inhibitors like olomoucine and roscovitine.

Another significant patent pertains to improving the effectiveness of cytotoxic drugs or radiotherapy using quinazolinone compounds. This invention features a variety of 3-oxybenzamide compounds, which serve as potent inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase (PARP). These compounds enhance the effectiveness of conventional DNA-damaging cytotoxic drugs and radiotherapy treatments.

Career Highlights

Alan H. Calvert has had a fulfilling career, lending his expertise to prominent institutions. Notably, he has worked with Newcastle University Ventures Limited and Cancer Research Campaign Technology Limited. His contributions have paved the way for advancements in therapeutic strategies targeting cancer treatment.

Collaborations

Throughout his career, Calvert has collaborated with esteemed colleagues, including Roger J. Griffin and David Richard Newell. These partnerships have been instrumental in driving forward innovative research and development in his field.

Conclusion

Alan H. Calvert's contributions to the realm of therapeutic inventions highlight the significant impact that dedicated inventors can make in advancing medical science. His patented work continues to offer promising solutions for the effective treatment of cancer and other diseases related to cell proliferation disorders.

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