Cincinnati, OH, United States of America

Alan D Cardin


 

Average Co-Inventor Count = 2.5

ph-index = 8

Forward Citations = 189(Granted Patents)


Company Filing History:


Years Active: 1989-2011

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26 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Alan D. Cardin in Medical Patents

Introduction

Alan D. Cardin, a prominent inventor based in Cincinnati, OH, has made significant strides in the field of medical sciences with an impressive portfolio of 26 patents. His innovations primarily focus on therapeutic applications that target critical health conditions such as heparin-induced thrombocytopenia (HIT) and its associated disease states.

Latest Patents

Among Cardin's latest patents are groundbreaking techniques utilizing dermatan sulfates and O-desulfated heparins. These inventions are designed to treat or prevent heparinoid-induced autoimmune responses, particularly targeting HIT. The dermatan sulfates feature repeating disulfated and trisulfated disaccharide units of L-iduronic acid and N-acetyl-D-galactosamine, exhibiting remarkable therapeutic potential. Cardin’s O-desulfated heparins are selectively altered to improve efficacy in medicinal applications, focusing on uronic acid and glucosamine saccharide residues. His research indicates that certain formulations, with a mean molecular weight ranging from about 2000 to about 10,000 Daltons, can effectively antagonize HIT.

Additionally, another inventive approach from Cardin combines a heparin cofactor II agonist with a platelet GPIIb/IIIa receptor antagonist. This synergistic application aims to inhibit platelet aggregation and thrombin generation, providing essential therapeutic advantages while significantly minimizing the risk of hemorrhagic side effects. The novel therapeutic regimen allows for the effective use of subtherapeutic doses, demonstrating Cardin's commitment to advancing medical treatments responsibly.

Career Highlights

Cardin has honed his expertise through notable tenures with reputable organizations, including Merrell Pharmaceuticals, Inc. and The Dow Chemical Company. His experience within these companies has greatly contributed to the collaborative environment from which his innovations stem. Alan’s dedication to enhancing medical treatment options through innovative research remains evident in his patent filings.

Collaborations

Throughout his career, Cardin has collaborated with several notable professionals in the field, including Michael J. Mullins and Richard L. Jackson. These partnerships have played a vital role in advancing his research and shaping his inventive solutions. Through cross-disciplinary teamwork, Cardin has continued to push the boundaries of medical innovation.

Conclusion

Alan D. Cardin exemplifies the spirit of innovation within the medical field, contributing significantly to advancements that have the potential to improve patient outcomes. His extensive collection of patents and collaborative efforts underscore his dedication to addressing complex health issues. As the medical community continues to evolve, Cardin’s work will undoubtedly remain influential in the ongoing pursuit of effective therapeutic solutions.

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