Company Filing History:
Years Active: 2017-2022
Title: Akinori Hishiya: Innovator in Protein Engineering
Introduction
Akinori Hishiya is a prominent inventor based in Belmont, MA (US). He has made significant contributions to the field of protein engineering, particularly in the development of fusion proteins that enhance protein expression and secretion.
Latest Patents
Hishiya holds 2 patents that focus on innovative approaches to protein production. His latest patents include "Cell-associated secretion-enhancing fusion proteins," which describe fusion proteins that comprise a target protein binding domain and a transmembrane retention domain. These proteins are engineered to be retained within the host cell, leading to an increased level of target protein secreted from the host cell. This innovation simplifies the purification process of the target protein and eliminates non-natural components from the extracellular media. Additionally, he has developed nucleic acid molecules encoding these fusion proteins for various applications, including restoring lost cell functions and treating diseases characterized by diminished cell function.
Another significant patent is related to "Protein expression enhancing polypeptides." This patent describes fusion proteins that link a protein expression enhancing polypeptide to a target protein binding domain. These innovations aim to enhance the expression and location of targeted proteins, restore lost functions in cells, and provide therapeutic solutions for diseases.
Career Highlights
Akinori Hishiya is currently associated with Sola Biosciences, LLC, where he continues to advance his research in protein engineering. His work has been instrumental in developing methods that enhance the secretion of co-expressed target proteins from host cells.
Collaborations
Hishiya collaborates with notable colleagues, including Keizo Koya and Luca Rastelli, to further his research and innovations in the field.
Conclusion
Akinori Hishiya's contributions to protein engineering through his innovative patents have the potential to significantly impact therapeutic applications and enhance our understanding of protein functions. His work exemplifies the importance of innovation in the life sciences.
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