This inventor holds 5 USPTO granted patents. Top assignee: California Institute of Technology. Active years: 2000-2011.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2000-2011
Title: Akiko Kumagai: Innovator in Cell Cycle Regulation
Introduction
Akiko Kumagai is a prominent inventor based in Altadena, CA (US). She has made significant contributions to the field of cell cycle regulation, holding a total of 5 patents. Her work focuses on understanding and modulating checkpoint activation, which is crucial for maintaining genomic integrity.
Latest Patents
One of her latest patents is titled "Methods for modulating checkpoint activation through TopBP1." This invention addresses the role of ATR kinase as a key regulator of checkpoint responses to incompletely replicated and damaged DNA. Without this checkpoint, cells may enter mitosis prematurely, leading to cell death. The invention provides methods and reagents to either block or activate the ATR kinase checkpoint by modulating the expression of the ATR activator TopBP1. Additionally, it includes screening methods to identify further TopBP1 inhibitors or activators that can be used to modulate ATR checkpoint activity.
Another significant patent is "Claspin proteins and methods of use thereof." This patent provides Claspin proteins and nucleotides encoding these proteins. It also outlines a method for identifying compounds that modulate cell cycle progression, as well as a method for modulating cell cycle progression itself.
Career Highlights
Akiko Kumagai is affiliated with the California Institute of Technology, where she continues her research and innovation in the field of cell biology. Her work has been instrumental in advancing our understanding of cell cycle checkpoints and their implications for cancer research.
Collaborations
She has collaborated with notable colleagues, including William G. Dunphy and Thomas R. Coleman, contributing to a rich environment of scientific inquiry and innovation.
Conclusion
Akiko Kumagai's contributions to the field of cell cycle regulation through her innovative patents highlight her role as a leading inventor. Her work not only enhances our understanding of cellular processes but also opens avenues for potential therapeutic interventions.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile