Akiko Doi

Title: Akiko Doi - Innovator in Genetic Therapeutics

Akiko Doi is a prominent inventor based in Boston, MA, known for her contributions to the field of genetic therapeutics. She has made significant strides in developing innovative solutions for genetic disorders, particularly those associated with the ABCA4 gene.

Latest Patents

Akiko Doi holds a patent for ABCA4 trans-splicing molecules. This patent describes nucleic acid trans-splicing molecules, including pre-mRNA trans-splicing molecules and RNA exon editing molecules. These molecules are designed to correct mutations in the ABCA4 gene, which are linked to disorders such as ABCA4-associated retinal dystrophies, including Stargardt Disease and cone-rod dystrophy. The patent outlines methods for using these molecules to treat disorders associated with mutations in ABCA4, highlighting their potential in the preparation of medicaments for these conditions.

Career Highlights

Doi is currently affiliated with Ascidian Therapeutics, Inc., where she continues to advance her research and development efforts. Her work focuses on innovative approaches to gene therapy, aiming to provide effective treatments for genetic disorders.

Collaborations

Some of her notable coworkers include Rebekka Krumbach and Scott J Dooley, who collaborate with her in various research initiatives.

Conclusion

Akiko Doi's work in developing ABCA4 trans-splicing molecules represents a significant advancement in the field of genetic therapeutics. Her contributions have the potential to transform the treatment landscape for patients with genetic disorders.